What Are Some Applications of In Situ Hybridization in Epidemiology?
ISH has numerous applications in epidemiological research, including:
Pathogen Detection: Identifying the presence of specific pathogens in tissue samples from infected individuals. Viral Load Assessment: Quantifying the amount of viral RNA or DNA in tissues to understand disease severity and progression. Host-Pathogen Interactions: Studying how pathogens interact with host cells and tissues, which can inform treatment strategies. Genomic Studies: Investigating genetic mutations, gene expression, and genomic alterations in various diseases. Cancer Research: Detecting specific genetic alterations and gene expression patterns in cancer tissues.