The incidence of ALS varies globally but is generally estimated to be between 1 to 2 cases per 100,000 people per year. The prevalence is around 5 to 7 cases per 100,000 people. The incidence and prevalence rates can be influenced by various factors, including age, gender, and geographical location. For example, ALS is more common in people aged 55 to 75 and is slightly more prevalent in men than in women.