What are the Risk Factors Associated with Neurofibrillary Tangles?

Several risk factors are linked to the development of NFTs and Alzheimer's disease. These include:

- Age: The most significant risk factor, with NFTs becoming more common as people age.
- Genetics: Certain genetic mutations and polymorphisms, such as those in the APOE gene, increase the risk of developing NFTs.
- Lifestyle Factors: Poor cardiovascular health, lack of physical activity, and poor diet can also contribute to the risk.
- Comorbidities: Conditions like diabetes and hypertension have been shown to increase the likelihood of NFT formation.