1. Data Collection: Gathering data from various sources including hospitals, surveys, and registries. 2. Estimations and Adjustments: Using statistical methods to adjust for underreporting and inconsistencies. 3. Use of Metrics: Employing metrics like DALYs, Years of Life Lost (YLLs), and Years Lived with Disability (YLDs) to quantify the burden. 4. Comparative Analysis: Comparing the burden across different regions, populations, and time periods.