The administration of TIG is particularly important for individuals who have not been fully vaccinated against tetanus or whose vaccination status is uncertain. It is also recommended for individuals with wounds that are particularly prone to infection, such as deep puncture wounds, wounds contaminated with dirt, feces, or saliva, and avulsions or crush injuries. In addition, individuals with compromised immune systems or those who have conditions that may impair wound healing may also be candidates for TIG.
