Tetanus Immune Globulin (TIG) is a preparation of antibodies derived from the plasma of donors who have been immunized against tetanus. These antibodies provide passive immunity by neutralizing the toxin produced by the bacterium Clostridium tetani. This is crucial in the context of wound management and post-exposure prophylaxis to prevent the development of tetanus, a serious and potentially fatal disease characterized by muscle stiffness and spasms.