Research has indicated that HCAs may be linked to several types of cancer, including colorectal, prostate, and breast cancer. For instance, studies have shown a correlation between high intake of well-done, fried, or barbecued meat and an increased risk of colorectal cancer. Similarly, there is evidence to suggest that HCAs may play a role in the development of prostate and breast cancer, although more research is needed to establish a definitive causal relationship.