Despite its utility, the OGTT has several limitations: 1. Inconvenience: The test requires fasting and multiple blood draws, which can be inconvenient for patients. 2. Cost: The OGTT can be expensive due to the need for laboratory testing and clinical oversight. 3. Variability: Factors such as stress, illness, and medication can affect glucose levels, potentially leading to false-positive or false-negative results. 4. Single-time Measurement: OGTT provides a snapshot of glucose metabolism at a single point in time, which may not reflect long-term glucose regulation.
