How Does Matrix Protein 2 Influence Viral Pathogenicity?
The M2 protein contributes to the pathogenicity of influenza A viruses by enabling the virus to infect host cells efficiently. The ion channel activity of M2 is critical for the viral uncoating process, which is a prerequisite for the replication of the virus. Any disruptions or mutations in the M2 protein can affect the virus's ability to infect and replicate, thereby influencing the severity and spread of the disease.
