Can Matrix Protein 2 Be a Target for Antiviral Drugs?
Yes, M2 is a well-known target for antiviral drugs. The most notable example is the class of drugs known as adamantanes, which includes amantadine and rimantadine. These drugs block the ion channel function of M2, preventing the acidification of the viral interior and thereby inhibiting viral replication. However, the widespread use of these drugs has led to the emergence of drug-resistant strains, highlighting the need for ongoing research and the development of new antiviral agents targeting M2.
