What Are the Challenges in Studying Tregs in Epidemiology?
One of the main challenges is the heterogeneity of Treg populations, which makes it difficult to define and measure them consistently across studies. Additionally, the functional plasticity of Tregs means they can adapt to different environmental conditions, complicating the interpretation of results. Another challenge is the potential for confounding factors, such as co-infections and genetic variability, which can influence Treg function and disease outcomes.
