Advantages: - High Specificity: FRNT specifically measures neutralizing antibodies, which are critical for protective immunity. - Quantitative: Provides a quantitative measure of antibody levels, allowing for precise comparisons. - Versatility: Can be adapted to various viruses and used in different settings.
Limitations: - Labor-Intensive: The test requires skilled personnel and sophisticated laboratory facilities. - Time-Consuming: The entire process can take several days to complete. - Biosafety Concerns: Working with live viruses necessitates appropriate biosafety measures to protect laboratory personnel.