There are thousands of rare conditions, some well-known and others less so. Examples include:
Cystic Fibrosis: A genetic disorder affecting the lungs and digestive system. Huntington's Disease: A progressive brain disorder caused by a single defective gene on chromosome 4. Gaucher's Disease: A genetic disorder where fatty substances accumulate in certain organs and tissues. Marfan Syndrome: A genetic disorder affecting connective tissue. Amyotrophic Lateral Sclerosis (ALS): A progressive neurodegenerative disease affecting nerve cells in the brain and spinal cord.