Several well-known genetic predispositions include:
- BRCA1 and BRCA2 Mutations: These mutations increase the risk of breast and ovarian cancers. - APOE-e4 Allele: Associated with a higher risk of Alzheimer's disease. - Factor V Leiden Mutation: Increases the risk of blood clots. - HLA-B27: Linked to a higher risk of autoimmune disorders like ankylosing spondylitis.