What are Some Common Driver Mutations in Different Cancers?
Several driver mutations are frequently observed in different types of cancer:
BRAF mutations are common in melanoma and colorectal cancer. KRAS mutations are prevalent in pancreatic, colorectal, and lung cancers. TP53 mutations are found in a wide range of cancers, including breast, lung, and ovarian cancers. PIK3CA mutations are seen in breast and endometrial cancers. ALK rearrangements are notable in NSCLC and anaplastic large cell lymphoma.