What are Integrase Strand Transfer Inhibitors (INSTIs)?
Integrase Strand Transfer Inhibitors (INSTIs) are a class of antiretroviral drugs used to treat Human Immunodeficiency Virus (HIV) infection. They work by inhibiting the activity of the HIV enzyme integrase, which is essential for the viral DNA to integrate into the host cell's genome. This mechanism effectively prevents the virus from replicating and spreading within the body.
