In the field of epidemiology, PROMIS is highly relevant as it provides robust tools for measuring health outcomes directly from patients. This is crucial for understanding the subjective experience of health and disease, which can complement traditional epidemiological measures like incidence and prevalence. PROMIS tools can be used in various study designs, including cross-sectional studies, cohort studies, and clinical trials, to assess the burden of disease, the effectiveness of interventions, and the quality of life.