HER2 status is typically determined using two main methods:
1. Immunohistochemistry (IHC): This test measures the amount of HER2 protein on the surface of cells in a breast cancer tissue sample. 2. Fluorescence In Situ Hybridization (FISH): This test looks for extra copies of the HER2 gene in cancer cells.
Both tests are important for accurately identifying HER2 status, which in turn influences treatment decisions.