To address ethical concerns, animal testing is tightly regulated by various government agencies and institutional review boards:
Institutional Animal Care and Use Committees (IACUCs): These committees oversee and evaluate all aspects of an institution's animal care and use program. Regulatory Guidelines: Guidelines such as the 3Rs Principle (Replacement, Reduction, and Refinement) aim to minimize the use of animals and ensure humane treatment. International Standards: Many countries adhere to international standards and agreements, such as the European Union's Directive 2010/63/EU on the protection of animals used for scientific purposes.