How Does SARS-CoV-2 Interact with the ACE2 Receptor?
The spike protein of SARS-CoV-2 binds to the ACE2 receptor on the surface of host cells. This binding facilitates the entry of the virus into cells, leading to infection. The high affinity of the SARS-CoV-2 spike protein for the ACE2 receptor is a key factor in the virus's ability to spread rapidly and infect a wide range of tissues, including the lungs, heart, and gastrointestinal tract.