What Are the Implications of ACE2 Expression Variability?
ACE2 receptor expression varies among different populations and tissues. Factors such as age, sex, genetic background, and underlying health conditions can influence the level of ACE2 expression. For example, higher levels of ACE2 expression have been observed in individuals with hypertension and diabetes, which may contribute to their increased susceptibility to severe COVID-19. Understanding these variations can help epidemiologists identify high-risk groups and tailor public health interventions accordingly.
