Adverse drug reactions can sometimes be predicted by specific HLA alleles. For example:
- Abacavir Hypersensitivity: HLA-B*57:01 is associated with hypersensitivity to abacavir, an antiretroviral drug used to treat HIV. - Carbamazepine-Induced Stevens-Johnson Syndrome: HLA-B*15:02 is linked to an increased risk of this severe skin reaction in certain populations.
