HLA genes influence the immune response to infectious diseases. For example:
- HIV: Certain HLA alleles, such as HLA-B*57 and HLA-B*27, are associated with slower disease progression in HIV-infected individuals. - Hepatitis B: Specific HLA alleles have been linked to either resistance or susceptibility to chronic Hepatitis B infection. - Malaria: Some HLA types can affect the severity and outcome of malaria infections.
