Public health authorities detained Mary Mallon in 1907, confining her to a quarantine facility on North Brother Island in New York. She was released in 1910 under the condition that she would no longer work as a cook. However, she defied this order, resulting in additional outbreaks. She was re-incarcerated in 1915 and remained in isolation until her death in 1938. This case underscores the importance of disease surveillance and quarantine measures in controlling infectious diseases.