What Markers are Typically Measured in Maternal Serum Screening?
Maternal serum screening measures several biomarkers, including Alpha-fetoprotein (AFP), Human Chorionic Gonadotropin (hCG), Unconjugated Estriol (uE3), and Inhibin-A. These markers are used in different combinations during the first and second trimesters to estimate the risk of specific conditions. For example, higher levels of hCG and Inhibin-A, along with lower levels of AFP and uE3, can indicate an increased risk of Down syndrome.
