What is the Role of HLA in Disease Susceptibility?

The variability in HLA genes among individuals and populations affects how people respond to infections and their susceptibility to various diseases. For instance, certain HLA alleles are linked to a higher risk of developing autoimmune diseases such as Type 1 Diabetes, rheumatoid arthritis, and celiac disease. HLA research helps in identifying these genetic predispositions, which can lead to better disease prevention strategies and personalized medicine approaches.