The MDRD Study Equation was developed from the MDRD Study, which aimed to explore the effects of dietary protein restriction and blood pressure control on the progression of renal disease. The equation estimates the eGFR based on serum creatinine levels, age, sex, and race. The standard MDRD equation is:
eGFR (mL/min/1.73m²) = 175 × (Serum Creatinine)^-1.154 × (Age)^-0.203 × (0.742 if female) × (1.212 if African American)