What is the Importance of Drug Excretion in Pharmacokinetics?
Drug excretion is the process of eliminating drugs from the body, primarily through the kidneys. Factors such as renal function, age, and comorbid conditions (like chronic kidney disease) can affect drug excretion rates. Epidemiological data on renal function across different populations help in adjusting drug dosages to prevent toxicity. For instance, elderly individuals often have reduced renal function, necessitating dose adjustments to avoid adverse effects.
