Single marker immunohistochemistry (IHC) is a laboratory technique used to detect specific antigens in tissue sections by using antibodies. This method relies on the principle of antigen-antibody binding, where a labeled antibody is used to visualize the presence and distribution of a particular antigen in the context of tissue morphology. In epidemiology, this technique is invaluable for understanding disease mechanisms, identifying biomarkers, and conducting population-based studies.
