parametric linkage analysis

What is Parametric Linkage Analysis?

Parametric linkage analysis is a statistical method used in genetic epidemiology to determine the approximate location of a gene that may contribute to a particular disease or trait. This approach relies on the assumption of a specific genetic model, including the mode of inheritance, allele frequencies, and penetrance. By analyzing family data, researchers can identify regions of the genome that co-segregate with the disease, thus pointing to the possible location of the responsible gene.

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