Cell-mediated immunity is a crucial aspect of the immune response where _T cells_ play a significant role in defending the body against intracellular pathogens. Unlike _humoral immunity_, which involves antibodies produced by B cells, cell-mediated immunity does not rely on antibodies. Instead, it involves the activation of phagocytes, antigen-specific cytotoxic T-lymphocytes, and the release of various _cytokines_ in response to an antigen.