Several factors can influence epidemiological trends, including: 1. Demographic Changes: Shifts in population age, gender, and ethnicity can affect disease patterns. 2. Environmental Factors: Changes in climate, urbanization, and pollution levels can influence the spread of certain diseases. 3. Behavioral Factors: Lifestyle choices, such as diet, physical activity, and substance use, can impact health outcomes. 4. Healthcare Access: Availability and quality of healthcare services play a significant role in disease prevention, detection, and treatment. 5. Genetic Factors: Genetic predispositions can affect susceptibility to certain diseases and conditions.