Several studies have investigated the efficacy of e-cigarettes for smoking cessation. A notable randomized controlled trial (RCT) published in the New England Journal of Medicine found that participants using e-cigarettes were more likely to quit smoking compared to those using nicotine replacement therapy (NRT) such as patches or gum. However, the study also noted that a significant proportion of e-cigarette users continued to use their devices after quitting traditional cigarettes, raising questions about long-term nicotine dependence.