Several risk factors can increase the likelihood of experiencing an ADR, including:
Age: Elderly and very young patients are more susceptible due to differences in drug metabolism and clearance. Genetics: Genetic variations can affect drug metabolism and response. Polypharmacy: The use of multiple medications increases the risk of drug-drug interactions and ADRs. Comorbidities: Conditions such as liver or kidney disease can impair drug metabolism. Previous history of ADRs: Patients who have experienced ADRs in the past are at higher risk.