Several serious adverse effects have been linked to NSAID use:
1. Gastrointestinal Issues: Long-term use can lead to gastrointestinal bleeding and ulcers. 2. Cardiovascular Risks: Some NSAIDs have been associated with an increased risk of heart attack and stroke. 3. Renal Impairment: Prolonged use can cause kidney damage, especially in individuals with pre-existing conditions. 4. Allergic Reactions: Some individuals may experience severe allergic reactions, including anaphylaxis.