Funding: Ensuring sustainable financing is a significant challenge, particularly for long-term projects. Coordination: Effective collaboration between various stakeholders is essential but can be difficult to achieve. Cultural Sensitivity: Interventions must be adapted to fit the cultural contexts of target populations. Data Collection and Analysis: Reliable epidemiological data is crucial for monitoring and evaluation, but data quality can vary significantly between regions. Political and Economic Stability: Unstable regions often face additional barriers to implementing health initiatives effectively.