Despite its strengths, NHANES has some limitations:
Cross-sectional Design: Because NHANES is cross-sectional, it captures data at a single point in time, making it difficult to establish causal relationships. Response Bias: As with any survey, there is the potential for response bias, particularly in self-reported data. Sample Size: While NHANES aims to be representative, the sample size may be insufficient for studying rare conditions or subpopulations in detail.