What Are the Challenges in Studying the HPA Axis in Epidemiology?
Studying the HPA axis in epidemiology presents several challenges: - Complex interactions among various biological systems make it difficult to isolate the effects of the HPA axis. - Variability in cortisol levels due to diurnal rhythms and external factors can complicate measurements. - Longitudinal studies are often required to understand the long-term effects of HPA axis dysregulation, which can be resource-intensive.