hypothalamic pituitary adrenal (hpa) axis

What Are the Challenges in Studying the HPA Axis in Epidemiology?

Studying the HPA axis in epidemiology presents several challenges:
- Complex interactions among various biological systems make it difficult to isolate the effects of the HPA axis.
- Variability in cortisol levels due to diurnal rhythms and external factors can complicate measurements.
- Longitudinal studies are often required to understand the long-term effects of HPA axis dysregulation, which can be resource-intensive.

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