Multi drug resistant bacteria are pathogens that have developed resistance to multiple classes of antibiotics. This resistance can occur through various mechanisms such as mutation, acquisition of resistant genes, or horizontal gene transfer. Common examples include Methicillin-resistant Staphylococcus aureus (MRSA), Extended-Spectrum Beta-Lactamases (ESBL) producing Enterobacteriaceae, and Carbapenem-resistant Enterobacteriaceae (CRE).