There are several strategies to mitigate temporal bias in epidemiological studies:
1. Prospective Study Design: Design studies prospectively to ensure that the temporal sequence of exposure and outcome is clear. 2. Clear Definitions: Clearly define the time windows for exposure and outcome assessment. 3. Statistical Adjustments: Use statistical methods to adjust for potential temporal misalignments. 4. Sensitivity Analyses: Perform sensitivity analyses to explore how different assumptions about timing affect the results.