How to Determine the Appropriate Follow-Up Duration?
Determining the appropriate follow-up duration involves balancing several considerations:
Scientific Justification: The duration should be scientifically justified based on the natural history of the disease and the expected time frame for the outcomes to manifest. Feasibility: Consider the practical aspects, such as funding, resources, and participant retention rates. Regulatory Guidelines: Adherence to ethical and regulatory guidelines, which may specify minimum follow-up periods for certain types of studies.
