How is Clinical Significance Different from Statistical Significance?
While statistical significance pertains to the probability that an observed effect is not due to chance, clinical significance evaluates the effect's real-world importance. For instance, a new drug might show a statistically significant reduction in blood pressure, but if this reduction is only by a couple of points, it may not be clinically significant. In epidemiology, it is crucial to distinguish between these two concepts to ensure that research findings translate into meaningful health improvements.