Researchers measure clinical significance using various approaches, such as:
1. Effect Size: This quantifies the magnitude of the treatment effect. Common measures include Cohen's d, Odds Ratios, and Relative Risks. 2. Number Needed to Treat (NNT): This represents the number of patients who need to be treated to prevent one additional adverse outcome. 3. Patient-Reported Outcomes (PROs): These are direct reports from patients about how they feel and function in relation to their health condition and its therapy.
