The primary mode of transmission of Plasmodium falciparum is through the bite of an infected Anopheles mosquito. When the mosquito bites an infected person, it ingests the parasite along with the blood meal. The parasite then undergoes development in the mosquito, and when the mosquito bites another human, it transmits the parasite into the bloodstream. Other, less common modes of transmission include blood transfusion, organ transplant, and the shared use of needles or syringes contaminated with infected blood.
