ART works by targeting various stages of the HIV life cycle. The regimen usually consists of a combination of at least three antiretroviral drugs from at least two different drug classes. This multifaceted approach helps to prevent the development of drug resistance. The main classes of antiretroviral drugs include Nucleoside Reverse Transcriptase Inhibitors (NRTIs), Non-nucleoside Reverse Transcriptase Inhibitors (NNRTIs), Protease Inhibitors (PIs), Integrase Inhibitors, and Entry/Fusion Inhibitors.