neutralization tests

How do Neutralization Tests Work?

Neutralization tests typically involve mixing a specific amount of a virus or bacterium with varying concentrations of serum from an individual. The mixture is then incubated and applied to a cell culture. If the antibodies present in the serum neutralize the pathogen, the cells will remain uninfected. The degree of neutralization is usually quantified by observing the reduction in cytopathic effects or plaque formation.

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