Several factors can contribute to participant burden in epidemiological studies:
1. Frequency and Length of Surveys: Frequent or lengthy surveys can be time-consuming and may discourage participation. 2. Complexity of Study Procedures: Complicated procedures, such as repeated blood draws or detailed dietary logs, can be physically and mentally taxing. 3. Invasiveness of Data Collection: Invasive procedures like biopsies or other medical tests can cause discomfort or pain. 4. Logistical Challenges: Issues such as travel requirements, appointment scheduling, and time off work can add to the burden. 5. Privacy Concerns: Concerns about the confidentiality of sensitive information may deter participation.