long latency periods:

How Do Long Latency Periods Affect Epidemiological Studies?

Long latency periods introduce several complexities into epidemiological research. These include:
Recall Bias: Individuals may not accurately remember past exposures, leading to data inaccuracies.
Confounding Factors: Over long periods, multiple exposures and lifestyle changes can occur, complicating the isolation of a single causative factor.
Longitudinal Studies: These require extensive time and resources to follow individuals over many years, increasing the cost and complexity of research.

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