Epidemiologists use various methods to study the effects of omega-3 fatty acids: 1. Cohort Studies - Following a group of individuals over time to observe the long-term effects of omega-3 intake. 2. Case-Control Studies - Comparing individuals with a specific condition to those without to identify dietary differences. 3. Randomized Controlled Trials (RCTs) - Assigning participants to receive either omega-3 supplements or a placebo to determine causality.