The determination of fixed dose adjustments is based on several factors:
Pharmacokinetics: The study of how drugs move through the body, including absorption, distribution, metabolism, and excretion. Pharmacodynamics: The study of the biological effects of drugs and their mechanisms of action. Patient Characteristics: Factors such as age, gender, body weight, organ function (e.g., kidney or liver function), and genetic profile. Comorbidities: Presence of other medical conditions that may affect drug metabolism and efficacy.
